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Article

Maintaining inhibition: siRNA double expression vectors against coxsackieviral RNAs.

Journal of molecular biology - 18 Feb 2005

Schubert Steffen, Grunert Hans-Peter, Zeichhardt Heinz, Werk Denise, Erdmann Volker A, Kurreck Jens

Abstract excerpt

The potential of RNA interference (RNAi) to inhibit virus propagation has been well established in recent years. In several studies, however, emergence of viral escape mutants after prolonged exposure to RNAi has been observed, raising a major hurdle for a possible therapeutic application of this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15670596
DOI: 10.1016/j.jmb.2004.11.074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15670596-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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