Article
Poliovirus escape from RNA interference: short interfering RNA-target recognition and implications for therapeutic approaches.
Journal of virology - 1 Jan 2005
Gitlin Leonid, Stone Jeffrey K, Andino Raul
Abstract excerpt
Short interfering RNAs (siRNAs) directed against poliovirus and other viruses effectively inhibit viral replication. Although RNA interference (RNAi) may provide the basis for specific antiviral therapies, the limitations of RNAi antiviral strategies are ill defined. Here, we show that poliovirus...
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