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Article

Selection of RNA replicons capable of persistent noncytopathic replication in mammalian cells.

Journal of virology - 1 May 1999

Frolov I, Agapov E, Hoffman T A, Prágai B M, Lippa M, Schlesinger S, Rice C M

Abstract excerpt

The natural life cycle of alphaviruses, a group of plus-strand RNA viruses, involves transmission to vertebrate hosts via mosquitoes. Chronic infections are established in mosquitoes (and usually in mosquito cell cultures), but infection of susceptible vertebrate cells typically results in rapid...

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Identifiers

PMID: 10196280
DOI: 10.1128/JVI.73.5.3854-3865.1999
PMCID: PMC104163

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-10196280-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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