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Article

Keratins as susceptibility genes for end-stage liver disease.

Gastroenterology - 1 Sept 2005

Ku Nam-On, Lim Joseph K, Krams Sheri M, Esquivel Carlos O, Keeffe Emmet B, Wright Teresa L, Parry David A D, Omary M Bishr

Abstract excerpt

BACKGROUND & AIMS: Keratins 8 and 18 protect the liver from stress. Keratin 8 and 18 variants in 17 of 467 liver disease explants and 2 of 349 blood bank controls were previously reported in 5 analyzed exonic regions. We asked whether mutations were present in the remaining 10 exons of keratins 8 and 18. METHODS: Exonic regions were polymerase chain reaction-amplified from genomic DNA, isolated from the...

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Share to Genetic Carrier Screening
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16143128
DOI: 10.1053/j.gastro.2005.06.065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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