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Article

Keratin variants associate with progression of fibrosis during chronic hepatitis C infection.

Hepatology (Baltimore, Md.) - 1 Jun 2006

Strnad Pavel, Lienau Tim C, Tao Guo-Zhong, Lazzeroni Laura C, Stickel Felix, Schuppan Detlef, Omary M Bishr

Abstract excerpt

Keratins 8 and 18 (K8/K18) protect the liver from various forms of injury. Studies of liver explants from a large cohort of U.S. patients showed that K8/K18 mutations confer a risk to developing end-stage liver diseases, though which diseases are preferentially involved is unknown. We tested the...

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Source

Identifiers

PMID: 16729313
DOI: 10.1002/hep.21211

Genes

KRT8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16729313-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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