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Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns.

Human genetics - 1 Nov 2005

Mohlke Karen L, Jackson Anne U, Scott Laura J, Peck Erin C, Suh Yong D, Chines Peter S, Watanabe Richard M, Buchanan Thomas A, Conneely Karen N, Erdos Michael R, Narisu Narisu, Enloe Sareena, Valle Timo T, Tuomilehto Jaakko, Bergman Richard N, Boehnke Michael, Collins Francis S

Abstract excerpt

Mitochondria play an integral role in ATP production in cells and are involved in glucose metabolism and insulin secretion, suggesting that variants in the mitochondrial genome may contribute to diabetes susceptibility. In a study of Finnish families ascertained for type 2 diabetes mellitus (T2DM), we genotyped single nucleotide polymorphisms (SNPs) based on phylogenetic networks. These SNPs defined eight major...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16142453
DOI: 10.1007/s00439-005-0046-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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