Article
Association study of mitochondrial DNA polymorphisms with type 2 diabetes in Tunisian population.
Mitochondrial DNA - 1 Jun 2015
Hsouna Sana, Ben Halim Nizar, Lasram Khaled, Arfa Imen, Jamoussi Henda, Bahri Sonia, Ammar Slim Ben, Miladi Najoua, Abid Abdelmajid, Abdelhak Sonia, Kefi Rym
Abstract excerpt
Mitochondrial DNA (mtDNA) variation may play an important role in the pathogenesis of type 2 diabetes (T2Ds). In this study, we aimed to explore whether mtDNA variants contribute to the susceptibility to T2Ds in a Tunisian population. The hypervariable region 1 (HVS1) of the mtDNA of 64 T2Ds patients and 77 healthy controls was amplified and sequenced. Statistical analysis was performed using the STATA program....
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