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Mitochondrial DNA coding and control region variants as genetic risk factors for type 2 diabetes.

Diabetes - 1 Oct 2012

Liou Chia-Wei, Chen Jin-Bor, Tiao Mao-Meng, Weng Shao-Wen, Huang Tiao-Lai, Chuang Jiin-Haur, Chen Shang-Der, Chuang Yao-Chung, Lee Wen-Chin, Lin Tsu-Kung, Wang Pei-Wen

Abstract excerpt

Both the coding and control regions of mitochondrial DNA (mtDNA) play roles in the generation of diabetes; however, no studies have thoroughly reported on the combined diabetogenic effects of variants in the two regions. We determined the mitochondrial haplogroup and the mtDNA sequence of the control region in 859 subjects with diabetes and 1,151 normoglycemic control subjects. Full-length mtDNA sequences were...

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Identifiers

PMID: 22891220
DOI: 10.2337/db11-1369
PMCID: PMC3447893

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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