Article
Parental diabetes status reveals association of mitochondrial DNA haplogroup J1 with type 2 diabetes.
BMC medical genetics - 18 Jun 2009
Feder Jeanette, Ovadia Ofer, Blech Ilana, Cohen Josef, Wainstein Julio, Harman-Boehm Ilana, Glaser Benjamin, Mishmar Dan
Abstract excerpt
BACKGROUND: Although mitochondrial dysfunction is consistently manifested in patients with Type 2 Diabetes mellitus (T2DM), the association of mitochondrial DNA (mtDNA) sequence variants with T2DM varies among populations. These differences might stem from differing environmental influences among populations. However, other potentially important considerations emanate from the very nature of mitochondrial...
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