Article
Novel variants of mitochondrial DNA associated with Type 2 diabetes mellitus in Moroccan population.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis - 1 Jan 2018
Charoute Hicham, Kefi Rym, Bounaceur Safaa, Benrahma Houda, Reguig Ahmed, Kandil Mostafa, Rouba Hassan, Bakhchane Amina, Abdelhak Sonia, Barakat Abdelhamid
Abstract excerpt
In this study, we investigated the association of mtDNA variants and haplogroups with Type 2 diabetes (T2D) in Moroccan patients. The Hypervariable Segments 1 of the mtDNA was sequenced in 108 diabetic patients and 97 controls. Association analyses were performed using Fisher's exact test and multivariate logistic regression. The prevalence of five mtDNA variants (C16187T, C16270T, T16172C, A16293G, and C16320T)...
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