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Article

Estrogen metabolizing polymorphisms and breast cancer risk among older white women.

Breast cancer research and treatment - 1 Oct 2005

Modugno Francesmary, Zmuda Joseph M, Potter Douglas, Cai Chao, Ziv Elad, Cummings Steven R, Stone Katie L, Morin Phillip A, Greene Deborah, Cauley Jane A

Abstract excerpt

OBJECTIVE: To investigate breast cancer risk according to metabolizing genes polymorphisms in older women. METHODS: A subset (43.8%) of 4248 older, white women from the Study of Osteoporotic Fractures (SOF) were genotyped for the catechol-O-methyltransferase (COMT) Val108Met polymorphism and the CYP1A1*2C locus. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals...

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Source

Identifiers

PMID: 16142442
DOI: 10.1007/s10549-005-5347-8

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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