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Article

Genetic polymorphisms in the catechol estrogen metabolism pathway and breast cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2009

Reding Kerryn W, Weiss Noel S, Chen Chu, Li Christopher I, Carlson Christopher S, Wilkerson Hui-Wen, Farin Federico M, Thummel Kenneth E, Daling Janet R, Malone Kathleen E

Abstract excerpt

BACKGROUND: This study investigated whether single nucleotide polymorphisms (SNP) in genes within the catechol estrogen metabolism pathway altered the risk of breast cancer alone or in combination, as well as whether menopausal hormone therapy modified the effect of these SNPs on breast cancer risk. METHODS: In a population-based case-control study of breast cancer, 891 cases and 878 controls were genotyped for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19383894
DOI: 10.1158/1055-9965.EPI-08-0917
PMCID: PMC2764317

Genes

GSTP1
COMT
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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