Article
Association of COMT Val158Met polymorphism and breast cancer risk: an updated meta-analysis.
Diagnostic pathology - 8 Oct 2012
Qin Xue, Peng Qiliu, Qin Aiping, Chen Zhiping, Lin Liwen, Deng Yan, Xie Li, Xu Juanjuan, Li Haiwei, Li Taijie, Li Shan, Zhao Jinmin
Abstract excerpt
BACKGROUND: Catechol-O-methyltransferase (COMT) is one of the most important enzymes involved in estrogen metabolism and its functional genetic polymorphisms may be associated with breast cancer (BC) risk. Many epidemiological studies have been conducted to explore the association between the COMT Val158Met polymorphism and breast cancer risk. However, the results remain inconclusive. In order to derive a more...
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