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Article

Catechol-O-Methyltransferase (COMT) gene polymorphism and breast cancer risk in young women.

British journal of cancer - 14 Sept 2001

Bergman-Jungeström M, Wingren S

Abstract excerpt

Oestrogen exposure has long been considered to be a main risk factor of breast cancer. More recently, interest has also focused on the possible carcinogenic influence from oestrogen metabolites, such as catechol oestrogens. O-methylation, catalysed by Catechol-O-Methyltransferase (COMT), is one pathway by which the potentially carcinogenic catechol oestrogens can be inactivated. The gene coding for COMT protein...

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Source

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Identifiers

PMID: 11556837
DOI: 10.1054/bjoc.2001.2009
PMCID: PMC2375076

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Catechol-O-Methyltransferase (COMT) gene polymorphism and breast cancer risk in young women.PMID 11556837Read ↗

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