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Genetic polymorphisms in estrogen-metabolizing genes and breast cancer survival.

Pharmacogenetics and genomics - 1 May 2007

Long Ji-Rong, Cai Qiuyin, Shu Xiao-Ou, Cai Hui, Gao Yu-Tang, Zheng Wei

Abstract excerpt

BACKGROUND: Estrogen plays a central role in the development and progression of breast cancer. The estrogen's effects are at least partially regulated by estrogen-metabolizing enzymes. The objective of the study is to investigate associations of breast cancer survival with genetic polymorphisms in several genes involved in estrogen metabolism (CYP1A1, CYP1A2, CYP1B1, COMT, and AhR). METHODS: A cohort of 1140...

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Source

Identifiers

PMID: 17429315
DOI: 10.1097/FPC.0b013e32801a3bfe

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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