Genetic etiology of oral cancer.

doi:10.1016/j.oraloncology.2017.05.004

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Article

Genetic etiology of oral cancer.

Oral oncology - 1 Jul 2017

Ali Johar, Sabiha Bibi, Jan Hanif Ullah, Haider Syed Adnan, Khan Abid Ali, Ali Saima S

Abstract excerpt

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide. It accounts for 2.5% of all new cancer cases and 1.9% of all cancer deaths annually. More than 90% of oral cancers (occurring in the mouth, lip, and tongue) are oral squamous cell carcinoma. The incidence rate of oral cancer varies widely throughout the world, with an evident prevalence in South Asian countries. This high...

Topics

Carcinoma, Squamous Cell
Cell Cycle Checkpoints
Epigenesis, Genetic
Genes, Tumor Suppressor
Genetic Predisposition to Disease
Humans
Loss of Heterozygosity
Mouth Neoplasms
Oncogenes
Receptors, Notch
Signal Transduction
Telomere

Source

Open in PubMed

Identifiers

PMID: 28622887
DOI: 10.1016/j.oraloncology.2017.05.004

Genes

APC
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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