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Article

Effect of sodium ferulate on human colonic anion secretion and the underlying signaling mechanism.

Biological & pharmaceutical bulletin - 1 Sept 2005

Zhao Wen Chao, Zhu Jin Xia, Zhang Gui Hong, Wong Connie Hau Yan, Chung Yiu Wa, Chan Hsiao Chang

Abstract excerpt

The present study investigated the effect of ferulic acid, a compound purified from traditional Chinese herbal medicine Chuanxiong and Awei, on anion secretion by human colonic cells (T84) using the short circuit current (I(SC)) and microspectrofluorimetric technique. Basolateral administration of sodium ferulate (SF) produced a concentration-dependent increase of I(SC) in T84 cells with an EC50 of 1.2 mM. The...

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PMID: 16141524
DOI: 10.1248/bpb.28.1608

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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