Article
Absorption of taurocholic acid by the ileum of normal and transgenic DeltaF508 cystic fibrosis mice.
The Journal of pharmacy and pharmacology - 1 Apr 2004
Hardcastle J, Harwood M D, Taylor C J
Abstract excerpt
Changes in intestinal transport in cystic fibrosis (CF) include both defective Cl(-) secretion and alterations in absorption. This study focused on the effects of CF on the active re-absorption of bile acids in the ileum of normal and transgenic CF mice. Taurocholic acid absorption was monitored as changes in short-circuit current (SCC) in intact and stripped ileal sheets from normal (Swiss) and transgenic CF...
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