Article
UTP regulation of ion transport in alveolar epithelial cells involves distinct mechanisms.
American journal of physiology. Lung cellular and molecular physiology - 1 Sept 2009
Yang Chuanxiu, Su Lijing, Wang Yang, Liu Lin
Abstract excerpt
UTP is known to regulate alveolar fluid clearance. However, the relative contribution of alveolar type I cells and type II cells to this process is unknown. In this study, we investigated the effects of UTP on ion transport in type I-like cell (AEC I) and type II-like cell (AEC II) monolayers. Luminal treatment of cell monolayers with UTP increased short-circuit current (I(sc)) of AEC II but decreased I(sc) of...
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