Article
Interleukin-13 induces a hypersecretory ion transport phenotype in human bronchial epithelial cells.
American journal of physiology. Lung cellular and molecular physiology - 1 Feb 2002
Danahay Henry, Atherton Hazel, Jones Gareth, Bridges Robert J, Poll Christopher T
Abstract excerpt
Interleukin (IL)-13 has been associated with asthma, allergic rhinitis, and chronic sinusitis, all conditions where an imbalance in epithelial fluid secretion and absorption could impact upon the disease. We have investigated the effects of IL-13 on the ion transport characteristics of human bronchial epithelial cells cultured at an apical-air interface. Ussing chamber studies indicated that 48 h pretreatment...
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