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Identification of Intestinal NaCl Absorptive-Anion Secretory Cells: Potential Functional Significance

19 Jul 2022

Abstract excerpt

Use of human enteroids studied in the undifferentiated and differentiated state that mimic the intestinal crypt and villus, respectively, has allowed studies of multiple enterocyte populations, including a large population of enterocytes that are transitioning from the crypt to the villus. This population expresses NHE3, DRA, and CFTR, representing a combination of Na absorptive and anion secretory functions. In...

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PMID: 35928564
DOI: 10.3389/fphys.2022.892112

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