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Article

Uncoupling between Ig somatic hypermutation and oncogene mutation in mouse lymphoma.

Biochimica et biophysica acta - 1 Feb 2009

Vincent Christelle, Truffinet Véronique, Fiancette Remi, Petit Barbara, Cogné Nadine, Cogné Michel, Denizot Yves

Abstract excerpt

Burkitt lymphoma (BL) features translocations linking c-myc to the immunoglobulin heavy chain (IgH) locus. By inserting a c-myc gene under the control of the 3'IgH locus control region (LCR) into the mouse genome, we generated c-myc-3'LCR mice that develop clonal BL or diffuse anaplastic lymphoma. We show in the present study that while BL from c-myc-3'LCR mice would be classified as pre-germinal center (GC)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19026697
DOI: 10.1016/j.bbamcr.2008.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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