Article
Interleukin 1 receptor antagonist gene polymorphism and risk of lung cancer: a possible interaction with polymorphisms in the interleukin 1 beta gene.
Lung cancer (Amsterdam, Netherlands) - 1 Dec 2005
Lind Helge, Zienolddiny Shanbeh, Ryberg David, Skaug Vidar, Phillips David H, Haugen Aage
Abstract excerpt
Tobacco smoking is the main risk factor for lung cancer. Only 10-15% of smokers develop lung cancer, suggesting that genetic factors are of importance in determining individual susceptibility to the disease. Several studies in recent years indicate that chronic inflammation is a cofactor in lung carcinogenesis. We have previously reported an association of interleukin 1 beta gene (IL1B) polymorphisms with lung...
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