Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A polymorphism of the interleukin-1 receptor antagonist plays a prominent role within the interleukin-1 gene cluster in vulvar carcinogenesis.

Gynecologic oncology - 1 Mar 2004

Grimm Christoph, Berger Ingrid, Tomovski Caroline, Zeillinger Robert, Concin Nicole, Leodolter Sepp, Koelbl Heinz, Tempfer Clemens B, Hefler Lukas A

Abstract excerpt

OBJECTIVE: The interleukin-1 (IL-1) family, that is, IL-1alpha and beta and the IL-1 receptor antagonist (IL-1RA), is known to modulate various tumorigenic and tumoricidal effects in humans. Its biological function in squamous cell carcinogenesis of various anatomical sites has been stressed. Although various studies showed a certain association between genes encoding the IL-1 family and human malignancies, no...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-1

Share to Interleukin 1 Receptor Antagonist Protein

Share to Multigene Family

Share to Neoplasm Staging

Share to Sialoglycoproteins

Share to Vulvar Neoplasms

Source

Identifiers

PMID: 14984963
DOI: 10.1016/j.ygyno.2003.11.039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A polymorphism of the interleukin-1 receptor antagonist plays a prominent role within the interleukin-1 gene cluster in vulvar carcinogenesis.PMID 14984963Read ↗

Polymorphism of IL-1 receptor antagonist gene: role in cancer.Semantic proximity Read ↗

Interleukin-1 and interleukin-6 gene polymorphisms and the risk of breast cancer in caucasian women.Semantic proximity Read ↗

Correlation of Interleukin-1 Receptor Antagonist (IL-1RA) gene polymorphisms in various cancersSemantic proximity Read ↗

IL1 receptor antagonist gene IL1-RN variable number of tandem repeats polymorphism and cancer risk: a literature review and meta-analysis.Semantic proximity Read ↗

Association of interleukin-1Ra gene polymorphism in patients with bladder cancer: case control study from North India.Semantic proximity Read ↗

Interleukin 1 receptor antagonist gene polymorphism and risk of lung cancer: a possible interaction with polymorphisms in the interleukin 1 beta gene.Semantic proximity Read ↗

Interleukin 1β and interleukin 1 receptor antagonist gene polymorphisms and cervical cancer: a meta-analysis.Semantic proximity Read ↗

Interleukin-1 Gene Cluster Polymorphisms and its Haplotypes may Predict the Risk to Develop Cervical Cancer in Tunisia.Semantic proximity Read ↗

A common interleukin-6 promoter polymorphism in patients with vulvar cancer.Semantic proximity Read ↗

Polymorphisms of the interleukin-1 gene cluster and ovarian cancer.Semantic proximity Read ↗

Genetic variants of interleukin-1RN and interleukin-1beta genes and risk of cervical cancer.Semantic proximity Read ↗

Impact of polymorphism in IL-1RA gene on the risk of cervical cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.