Article
Polymorphisms of the interleukin-1 beta gene are associated with increased risk of non-small cell lung cancer.
International journal of cancer - 10 Apr 2004
Zienolddiny Shanbeh, Ryberg David, Maggini Valentina, Skaug Vidar, Canzian Federico, Haugen Aage
Abstract excerpt
Lung cancer is one of the leading causes of cancer death worldwide. Tobacco smoking is the main risk factor for lung cancer. Less than 20% of smokers develop lung cancer in their lifetime, however, indicating individual variations in lung cancer risk. Pro-inflammatory cytokines produced by inflammatory cells have been associated with inflammatory diseases and cancer. The IL1B gene, encoding IL-1beta cytokine,...
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