Article
Association between polymorphism of interleukin-1 beta and interleukin-1 receptor antagonist gene and asthma risk: a meta-analysis.
TheScientificWorldJournal - 1 Jan 2015
He Yuanzhou, Peng Shuang, Xiong Weining, Xu Yongjian, Liu Jin
Abstract excerpt
BACKGROUND: Asthma is a complex polygenic disease in which gene-environment interactions are important. A number of studies have investigated the polymorphism of IL-1β -511C/T and IL-1RA genes in relation to asthma susceptibility in different populations. However, the results of individual studies have been inconsistent. Accordingly, we conducted a comprehensive meta-analysis to investigate the association...
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