Article
Interleukin-1R antagonist gene and pre-natal smoke exposure are associated with childhood asthma.
The European respiratory journal - 1 Mar 2007
Ramadas R A, Sadeghnejad A, Karmaus W, Arshad S H, Matthews S, Huebner M, Kim D-Y, Ewart S L
Abstract excerpt
The interleukin-1 receptor antagonist (IL1RN) is a potent anti-inflammatory cytokine. In the present study, association of the human IL1RN gene polymorphisms with asthma, bronchial hyperresponsiveness and forced expiratory volume in one second/forced vital capacity ratio was tested and the data was stratified by environmental tobacco smoke exposure in order to investigate a gene-smoking interaction. In an...
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