Article
The Optimedin gene is a downstream target of Pax6.
The Journal of biological chemistry - 21 Oct 2005
Grinchuk Oleg, Kozmik Zbynek, Wu Xiaofang, Tomarev Stanislav
Abstract excerpt
The Optimedin gene, also known as Olfactomedin 3, encodes an olfactomedin domain-containing protein. There are two major splice variants of the Optimedin mRNA, Optimedin A and Optimedin B, transcribed from different promoters. The expression pattern of the Optimedin A variant in the eye and brain overlaps with that for Pax6, which encodes a protein containing the paired and homeobox DNA-binding domains. The Pax6...
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