Article
The expression of Pax6 variants is subject to posttranscriptional regulation in the developing mouse eyelid.
PloS one - 1 Jan 2013
Shi Fangyu, Fan Yannan, Zhang Laiguang, Meng Lu, Zhi Huifang, Hu Hongyu, Lin Aixin
Abstract excerpt
Pax6 is a pivotal transcription factor that plays a role during early eye morphogenesis, but its expression and function in eyelid development remain unknown. In this study, the expression patterns of Pax6 mRNA and protein were examined in the developing mouse eyelid at embryonic days 14.5, 15.5, and 16.5. The function of Pax6 in eyelid development was determined by comparing it to that in the eyes-open-at-birth...
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