Article
Genetic and biochemical diversity in the Pax gene family.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Jan 2000
Underhill D A
Abstract excerpt
The mammalian Pax gene family comprises nine members that are characterized by a conserved DNA-binding motif, the paired domain, which was originally described in the Drosophila protein paired. Both loss- and gain-of-function studies reveal that Pax genes carry out essential roles during embryogenesis, and in some instances, may function as master regulatory genes. This review focuses on both genetic and...
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