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Article

A screen for proteins that interact with PAX6: C-terminal mutations disrupt interaction with HOMER3, DNCL1 and TRIM11.

BMC genetics - 12 Aug 2005

Cooper Simon T, Hanson Isabel M

Abstract excerpt

BACKGROUND: The PAX6 protein is a transcriptional regulator with a key role in ocular and neurological development. Individuals with heterozygous loss-of-function mutations in the PAX6 gene have malformations of the eye and brain. Little is known about the interactions of PAX6 with other proteins, so we carried out a systematic screen for proteins that interact with PAX6. RESULTS: We used bioinformatics...

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Source

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Identifiers

PMID: 16098226
DOI: 10.1186/1471-2156-6-43
PMCID: PMC1208879

Genes

PAX6
HOMER3
TRIM11
PSD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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