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Article

Evolution of functional diversification of the paired box (Pax) DNA-binding domains.

Molecular biology and evolution - 1 Aug 1997

Balczarek K A, Lai Z C, Kumar S

Abstract excerpt

The Pax gene family consists of tissue-specific transcriptional regulators that always contain a highly conserved DNA-binding domain with six alpha-helices (paired domain), and, in many cases, a complete or residual homeodomain. Numerous genes of this family have been identified in animals, with the largest number found in vertebrates. Our evolutionary analyses indicate that the vertebrate Pax gene family...

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PMID: 9254921
DOI: 10.1093/oxfordjournals.molbev.a025824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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