Article
PAX6 in sensory development.
Human molecular genetics - 15 May 2002
van Heyningen Veronica, Williamson Kathleen A
Abstract excerpt
PAX6 function was first identified through aniridia-associated null mutations. Since then, this transcription factor, with a paired domain and a homeodomain, has become a paradigm, illustrating functional conservation in developmental pathways. The Small eye mouse and Drosophila eyeless have served as major model systems in defining the multistage roles for Pax6 in eye and olfactory system development throughout...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.