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Article

Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis.

Cancer research - 1 Jul 2005

Zhao Xiaojun, Weir Barbara A, LaFramboise Thomas, Lin Ming, Beroukhim Rameen, Garraway Levi, Beheshti Javad, Lee Jeffrey C, Naoki Katsuhiko, Richards William G, Sugarbaker David, Chen Fei, Rubin Mark A, Jänne Pasi A, Girard Luc, Minna John, Christiani David, Li Cheng, Sellers William R, Meyerson Matthew

Abstract excerpt

Genome-wide copy number changes were analyzed in 70 primary human lung carcinoma specimens and 31 cell lines derived from human lung carcinomas, with high-density arrays representing approximately 115,000 single nucleotide polymorphism loci. In addition to previously characterized loci, two regions of homozygous deletion were found, one near the PTPRD locus on chromosome segment 9p23 in four samples representing...

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Source

Identifiers

PMID: 15994928
DOI: 10.1158/0008-5472.CAN-04-4603

Genes

EGFR
ERBB2
FGFR1
MET
PTPRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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