Article
Dendritic cells from chronic lymphocytic leukemia patients are normal regardless of Ig V gene mutation status.
Molecular medicine (Cambridge, Mass.) - 1 Jan 2000
Messmer Davorka, Telusma Gloria, Wasil Tarun, Messmer Bradley T, Allen Steven, Rai Kanti R, Chiorazzi Nicholas
Abstract excerpt
Patients with B-type chronic lymphocytic leukemia (B-CLL) segregate into 2 subgroups based on the mutational status of the immunoglobulin (Ig) V genes and the patients in these subgroups follow very different clinical courses. To examine whether dendritic cells (DCs) generated from CLL patients can be candidates for immune therapy, we compared the phenotypic and functional capacities of DCs generated from...
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