Article

Profound deficiencies in mature blood and bone marrow progenitor dendritic cells in Chronic Lymphocytic Leukemia patients

2024-09-27

Abstract excerpt

<title>Abstract</title> <p>Chronic lymphocytic leukemia (CLL) patients are immunocompromised and highly vulnerable to serious recurrent infections. Conventional dendritic cells (cDCs) and plasmacytoid DCs (pDCs) are principal sensors of infection and are essential in orchestrating innate and adaptive immune responses to resolve infection. This study identified significant deficiencies in six functionally distinct...

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Literature Corpus work: c4125159-ff30-551e-b360-cc8c149d9583
DOI: 10.21203/rs.3.rs-4953853/v1

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