Generation of mature dendritic cells with unique phenotype and function by in vitro short-term culture of human monocytes in the presence of interleukin-4 and interferon-beta.

doi:10.3181/0712-RM-333

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Generation of mature dendritic cells with unique phenotype and function by in vitro short-term culture of human monocytes in the presence of interleukin-4 and interferon-beta.

Experimental biology and medicine (Maywood, N.J.) - 1 Jun 2008

Zhang Li Feng, Okuma Kazu, Tanaka Reiko, Kodama Akira, Kondo Kayo, Ansari Aftab A, Tanaka Yuetsu

Abstract excerpt

Dendritic cell (DC)-based immunotherapy has been utilized for the treatment of not only a number of human malignancies but also a select group of infectious diseases. Conventional techniques for the generation and maturation of DCs require 7 days of in vitro culture, which prompted us to seek alternative methods that would hasten the generation of functional human myeloid DCs in vitro. Following the use of a...

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Generation of mature dendritic cells with unique phenotype and function by in vitro short-term culture of human monocytes in the presence of interleukin-4 and interferon-beta.

Abstract excerpt

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Generation of mature dendritic cells with unique phenotype and function by in vitro short-term culture of human monocytes in the presence of interleukin-4 and interferon-beta.

Abstract excerpt

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