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Article

Type 1-polarized dendritic cells loaded with autologous tumor are a potent immunogen against chronic lymphocytic leukemia.

Journal of leukocyte biology - 1 Jul 2008

Lee Je-Jung, Foon Kenneth A, Mailliard Robbie B, Muthuswamy Ravikumar, Kalinski Pawel

Abstract excerpt

Induction of active tumor-specific immunity in patients with chronic lymphocytic leukemia (CLL) and other hematologic malignancies is compromised by the deficit of endogenous dendritic cells (DCs). In attempt to develop improved vaccination strategies for patients with CLL and other tumors with poorly identified rejection antigens, we tested the ability of ex vivo-generated DCs to cross-present the antigens...

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Source

Open in PubMed Open full text

Identifiers

PMID: 18426971
DOI: 10.1189/jlb.1107737
PMCID: PMC2908026

Genes

TNF
CCR7
CD40
CD80
CD83
CD86

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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