Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasmacytoids dendritic cells are a therapeutic target in anticancer immunity.

Biochimica et biophysica acta - 1 Dec 2012

Palma Giuseppe, De Laurenzi Vincenzo, De Marco Margot, Barbieri Antonio, Petrillo Antonella, Turco Maria Caterina, Arra Claudio

Abstract excerpt

Dendritic cells (DCs) are immunological sentinels of the organism acting as antigen-presenting cells (APC) and are critical for induction of innate and adaptive immunity. Traditionally they are divided in myeloid dendritic cells (mDCs) and plasmacytoid dendritic cells (pDCs), a rare population of circulating cells that selectively express Toll-like receptors (TLR) 7 and TLR9 and have the capacity to produce large...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clinical Trials as Topic
Share to Dendritic Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to TLR9 gene

Share to Neoplasms

Share to Phenotype

Share to Receptors, Immunologic

Share to Signal Transduction

Share to Toll-Like Receptors

Source

Identifiers

PMID: 22579960
DOI: 10.1016/j.bbcan.2012.04.007

Genes

APC
BST2
LILRA4
TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasmacytoids dendritic cells are a therapeutic target in anticancer immunity.PMID 22579960Read ↗

Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses.Semantic proximity Read ↗

Phenotypic and functional differences of dendritic cells in tumor.Semantic proximity Read ↗

Tumoricidal activity of human dendritic cells.Semantic proximity Read ↗

Phenotypes and Functions of Human Dendritic Cell Subsets in the Tumor Microenvironment.Semantic proximity Read ↗

Dendritic cells: phenotypic and functional heterogeneity.Semantic proximity Read ↗

Dendritic Cells in the Context of Human Tumors: Biology and Experimental ToolsSemantic proximity Read ↗

Dendritic Cells and Their Role in Immunotherapy.Semantic proximity Read ↗

CD2 distinguishes two subsets of human plasmacytoid dendritic cells with distinct phenotype and functions.Semantic proximity Read ↗

Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interactionSemantic proximity Read ↗

Human plasmacytoid dendritic cells efficiently cross-present exogenous Ags to CD8+ T cells despite lower Ag uptake than myeloid dendritic cell subsetsSemantic proximity Read ↗

Human dendritic cell subsets: an update.Semantic proximity Read ↗

Opposing Roles of Dectin-1 Expressed on Human Plasmacytoid Dendritic Cells and Myeloid Dendritic Cells in Th2 PolarizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.