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Article

Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype.

Scientific reports - 19 Jul 2016

Harfuddin Zulkarnain, Dharmadhikari Bhushan, Wong Siew Cheng, Duan Kaibo, Poidinger Michael, Kwajah Shaqireen, Schwarz Herbert

Abstract excerpt

The importance of monocyte-derived dendritic cells (DCs) is evidenced by the fact that they are essential for the elimination of pathogens. Although in vitro DCs can be generated by treatment of monocytes with GM-CSF and IL-4, it is unknown what stimuli induce differentiation of DCs in vivo. CD137L-DCs are human monocyte-derived DC that are generated by CD137 ligand (CD137L) signaling. We demonstrate that the...

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Identifiers

PMID: 27431276
DOI: 10.1038/srep29712
PMCID: PMC4949477

Genes

ALCAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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