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Article

Brain structure in preclinical Huntington's disease.

Biological psychiatry - 1 Jan 2006

Paulsen Jane S, Magnotta Vince A, Mikos Ania E, Paulson Henry L, Penziner Elizabeth, Andreasen Nancy C, Nopoulos Peg C

Abstract excerpt

BACKGROUND: Huntington's disease (HD) is traditionally conceptualized as a degenerative disease of the striatum. Recent scientific advances, however, have suggested neurodevelopmental contributions and extrastriatal brain abnormalities. This study was designed to assess the morphology of the brain in participants who had previously undergone elective DNA analyses for the HD mutation who did not currently have a...

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Identifiers

PMID: 16112655
DOI: 10.1016/j.biopsych.2005.06.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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