Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decreased diffusivity in the caudate nucleus of presymptomatic huntington disease gene carriers: which explanation?

AJNR. American journal of neuroradiology - 1 Apr 2010

Mandelli M L, Savoiardo M, Minati L, Mariotti C, Aquino D, Erbetta A, Genitrini S, Di Donato S, Bruzzone M G, Grisoli M

Abstract excerpt

BACKGROUND AND PURPOSE: The neostriatum is known to be affected in HD. In this work, our aim was to determine whether microstructural and volumetric alterations occur in the neostriatum of presymptomatic HD gene carriers and in patients with early-stage HD. MATERIALS AND METHODS: We studied a group of 15 presymptomatic gene carriers who were far from the estimated symptom onset (16% probability of developing the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caudate Nucleus
Share to Diffusion Magnetic Resonance Imaging

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Early Diagnosis

Share to Genetic Carrier Screening

Share to Huntington Disease

Share to Image Processing, Computer-Assisted

Share to Putamen

Share to Reference Values

Source

Open in PubMed Open full text

Identifiers

PMID: 19942704
DOI: 10.3174/ajnr.A1891
PMCID: PMC7964218

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decreased diffusivity in the caudate nucleus of presymptomatic huntington disease gene carriers: which explanation?PMID 19942704Read ↗

Huntingtonʼs diseaseSemantic proximity Read ↗

Prefrontal cortex white matter tracts in prodromal Huntington disease.Semantic proximity Read ↗

Brain structure in preclinical Huntington's disease.Semantic proximity Read ↗

Timing of selective basal ganglia white matter loss in Huntington’s diseaseSemantic proximity Read ↗

Reduced basal ganglia blood flow and volume in pre-symptomatic, gene-tested persons at-risk for Huntington's disease.Semantic proximity Read ↗

Regional distribution and clinical correlates of white matter structural damage in Huntington disease: a tract-based spatial statistics study.Semantic proximity Read ↗

Striatal and extrastriatal atrophy in Huntington's disease and its relationship with length of the CAG repeat.Semantic proximity Read ↗

In vivo mapping of striatal neurodegeneration in Huntington’s disease with Soma and Neurite Density ImagingSemantic proximity Read ↗

Longitudinal imaging highlights preferential basal ganglia circuit atrophy in Huntington’s diseaseSemantic proximity Read ↗

Biological and clinical characteristics of gene carriers far from predicted onset in the Huntington's disease Young Adult Study (HD-YAS): a cross-sectional analysisSemantic proximity Read ↗

Natural biological variation of white matter microstructure is accentuated in Huntington's disease.Semantic proximity Read ↗

Longitudinal cognitive and motor changes among presymptomatic Huntington disease gene carriers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.