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Article

Relationship between CAG repeat length and brain volume in premanifest and early Huntington's disease.

Journal of neurology - 1 Feb 2009

Henley Susie M D, Wild Edward J, Hobbs Nicola Z, Scahill Rachael I, Ridgway Gerard R, Macmanus David G, Barker Roger A, Fox Nick C, Tabrizi Sarah J

Abstract excerpt

Huntington's disease (HD) is caused by an expanded CAG repeat on the gene encoding for the protein huntingtin. There are conflicting findings about the extent to which repeat length predicts signs of the disease or severity of disease progression in adults. This study examined the relationship between CAG repeat length and brain volume in a large cohort of pre- and post-motor onset HD gene carriers, using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19266143
DOI: 10.1007/s00415-009-0052-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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