Article
Morphology of the cerebral cortex in preclinical Huntington's disease.
The American journal of psychiatry - 1 Sept 2007
Nopoulos Peg, Magnotta Vincent A, Mikos Ania, Paulson Henry, Andreasen Nancy C, Paulsen Jane S
Abstract excerpt
OBJECTIVE: Cortical morphology was evaluated in subjects with known gene expansion for Huntington's disease and no manifest disease. METHOD: Magnetic resonance imaging scans were obtained for 24 subjects with preclinical Huntington's disease and were compared to those for 24 matched healthy subjects by means of novel imaging methods to quantify aspects of cortical structure. RESULTS: In relation to the comparison...
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