Article
Topography of cerebral atrophy in early Huntington's disease: a voxel based morphometric MRI study.
Journal of neurology, neurosurgery, and psychiatry - 1 Feb 2004
Kassubek J, Juengling F D, Kioschies T, Henkel K, Karitzky J, Kramer B, Ecker D, Andrich J, Saft C, Kraus P, Aschoff A J, Ludolph A C, Landwehrmeyer G B
Abstract excerpt
OBJECTIVES: To analyse grey matter changes in early stages of Huntington's disease using magnetic resonance imaging (MRI) and the technique of voxel based morphometry (VBM). METHODS: Forty four patients with a molecularly confirmed clinical diagnosis of Huntington's disease based on the presence of motor signs were included in the study. Patients were clinically rated using the Unified Huntington's Disease Rating...
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