Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Longitudinal analysis of regional grey matter loss in Huntington disease: effects of the length of the expanded CAG repeat.

Journal of neurology, neurosurgery, and psychiatry - 1 Feb 2008

Ruocco H H, Bonilha L, Li L M, Lopes-Cendes I, Cendes F

Abstract excerpt

BACKGROUND: The mechanisms guiding the progression of neuronal damage in patients with Huntington disease (HD) are not completely understood. It is unclear whether the genotype--that is, the length of the expanded CAG repeat--guides the location and speed of grey matter decline once HD is clinically manifested. Moreover, the relationship between cortical and subcortical grey matter atrophy and the severity of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atrophy
Share to DNA Repeat Expansion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Huntington Disease

Share to Image Processing, Computer-Assisted

Share to Imaging, Three-Dimensional

Share to Neurologic Examination

Share to Statistics as Topic

Share to Trinucleotide Repeats

Source

Identifiers

PMID: 17615168
DOI: 10.1136/jnnp.2007.116244

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Longitudinal analysis of regional grey matter loss in Huntington disease: effects of the length of the expanded CAG repeat.PMID 17615168Read ↗

Relationship between CAG repeat length and brain volume in premanifest and early Huntington's disease.Semantic proximity Read ↗

Longitudinal imaging highlights preferential basal ganglia circuit atrophy in Huntington’s diseaseSemantic proximity Read ↗

Clinical presentation and patterns of regional cerebral atrophy related to the length of trinucleotide repeat expansion in patients with adult onset Huntington's disease.Semantic proximity Read ↗

Association of CAG Repeats With Long-term Progression in Huntington DiseaseSemantic proximity Read ↗

Distinct brain volume changes correlating with clinical stage, disease progression rate, mutation size, and age at onset prediction as early biomarkers of brain atrophy in Huntington's disease.Semantic proximity Read ↗

Striatal volume loss in HD as measured by MRI and the influence of CAG repeatSemantic proximity Read ↗

Huntingtin CAG repeat is a continuous modifier of brain structure and health vulnerabilitySemantic proximity Read ↗

Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data.Semantic proximity Read ↗

Striatal and extrastriatal atrophy in Huntington's disease and its relationship with length of the CAG repeat.Semantic proximity Read ↗

Topography of cerebral atrophy in early Huntington's disease: a voxel based morphometric MRI study.Semantic proximity Read ↗

Dynamics of cortical degeneration over a decade in Huntington’s DiseaseSemantic proximity Read ↗

Volumetric MRI-Based Biomarkers in Huntington's Disease: An Evidentiary ReviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.