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Article

Demographic, environmental, and genetic predictors of metabolic side effects of hydrochlorothiazide treatment in hypertensive subjects.

American journal of hypertension - 1 Aug 2005

Maitland-van der Zee Anke-Hilse, Turner Stephen T, Schwartz Gary L, Chapman Arlene B, Klungel Olaf H, Boerwinkle Eric

Abstract excerpt

BACKGROUND: Thiazide diuretics are recommended for first-line treatment of hypertension. Although considered safe and effective, their use is associated with dyslipidemia, hyperglycemia, and an increased risk of developing type 2 diabetes. The aim of this study was to characterize interindividual variation in glucose and lipid responses to hydrochlorothiazide and to identify demographic, environmental, and...

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Identifiers

PMID: 16109321
DOI: 10.1016/j.amjhyper.2005.02.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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