Article
Genetic predictors of thiazide-induced serum potassium changes in nondiabetic hypertensive patients.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Aug 2014
Huang Chin-Chou, Chung Chia-Min, Hung Shuen-Iu, Leu Hsin-Bang, Lin Liang-Yu, Huang Po-Hsun, Wu Tao-Cheng, Lin Shing-Jong, Pan Wen-Harn, Chen Jaw-Wen
Abstract excerpt
Thiazide diuretics are associated with an increased risk of hypokalemia. However, pharmacogenetic markers of thiazide-induced changes in serum potassium are not well studied. The aim of this study was to investigate possible predictors of serum potassium changes after thiazide treatment. Nondiabetic hypertensive patients with a systolic blood pressure of ⩾140 or a diastolic blood pressure of ⩾90 mm Hg were...
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