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Article

Mechanism of up-regulation of immunoglobulin A production in the intestine of mice unresponsive to lipopolysaccharide.

Immunology - 1 Sept 2005

Kaneko Masahiro, Akiyama Yoshiyuki, Takimoto Hiroaki, Kumazawa Yoshio

Abstract excerpt

The mechanisms by which immunoglobulin A (IgA) production up-regulates in the intestine of Toll-like receptor-4 (TLR4)-mutated mice were investigated. When TLR4-mutated, C3H/HeJ and BALB/lps(d) mice received oral administration of cholera toxin (CT), not only CT-specific IgA levels in the intestinal lavage but also the number of IgA-producing cells in intestinal lamina propria (iLP) significantly increased...

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Share to Antigen Presentation
Share to Immune Tolerance
Share to Immunity, Mucosal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin A

Share to Intestine, Small

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Share to Suppressor of Cytokine Signaling 1 Protein

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Source

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Identifiers

PMID: 16108818
DOI: 10.1111/j.1365-2567.2005.02198.x
PMCID: PMC1802409

Genes

TLR4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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