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Article

TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements.

The Journal of biological chemistry - 4 Nov 2005

Nishiya Tadashi, Kajita Emi, Miwa Soichi, Defranco Anthony L

Abstract excerpt

Toll-like receptor (TLR) 3 and TLR7 are indispensable for host defense against viral infection by recognizing virus-derived RNAs and are localized to intracellular membranes via an unknown mechanism. We recently reported experiments with chimeric Toll-like receptors that suggested that the subcellular distribution of TLRs may be defined by their transmembrane and/or cytoplasmic domains. Here we demonstrate that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16105838
DOI: 10.1074/jbc.M504951200

Genes

TLR7
TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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